What's Hydroxyapatite Toothpaste and Why Is It Suddenly Everywhere?

A few years ago, barely anyone talked about hydroxyapatite toothpaste like Boka toothpaste. Now? It’s all over your feed. On TikTok, on Reddit, and even in dentist offices. What changed?

For starters, people are looking for cleaner, safer options. They’re tired of long ingredient lists and warnings they don’t understand. Hydroxyapatite sounds fancy, but it’s actually what your teeth are made of.

That’s the hook. It works with your body, not against it. And unlike fluoride, it doesn’t come with health concerns or risk if swallowed.

People want toothpaste that works. They want to protect their teeth without side effects. That’s why this ingredient is getting so much attention.

What Is Hydroxyapatite?

Hydroxyapatite is a form of calcium that’s naturally found in your teeth and bones. It’s what gives enamel its strength.

The version used in toothpaste is synthetic, but it's made to mimic the real thing. When applied to your teeth, it fills in tiny holes and repairs surface damage. That means smoother enamel, less sensitivity, and better protection.

And yes, it’s safe to swallow. That's one reason it’s used in Japan and Europe more than fluoride.

Best Hydroxyapatite Toothpastes to Try in 2025

There are a lot of options out there. We’ve tested several of these ourselves and read more reviews than we care to admit. Below are some of the top picks that stand out for their clean ingredients, great performance, and, when possible, sustainability.

Boka Ela Mint Toothpaste

This is one of the top hydroxyapatite toothpastes on the market right now, and for good reason. Boka toothpaste has got a gentle mint flavor, not too strong, and leaves your mouth feeling fresh without that dry, stripped feeling.

Boka toothpaste uses nano-hydroxyapatite and keeps the rest of the ingredient list clean and simple. It’s fluoride-free, vegan, and cruelty-free. While their packaging isn’t fully plastic-free yet, they’re transparent about their sourcing and committed to reducing waste across their supply chain.

Price: $11.69 for 1 tube (4 fl oz)

Get it on Amazon | Get it on Boka

Davids Nano-Hydroxyapatite Toothpaste

Davids really nails it on sustainability. It comes in a recyclable metal tube and an FSC-certified paper box, includes a metal key to help squeeze it out, and avoids plastic wherever possible.

The brand uses nano-hydroxyapatite in its clean, USA-made formula to support enamel and reduce sensitivity without any fluoride, SLS, or artificial ingredients. The texture is smooth, and the mint is a little stronger than Boka toothpaste, which I liked for that extra clean feel. It also includes xylitol for added oral bacteria support.

Price: $11.95 for 1 tube (5.25 oz)
Get it on Grove

DentaViva Hydroxyapatite Toothpaste

DentaViva might also be new to the scene, but this formula hits hard. It uses 5% nano-hydroxyapatite – more than most brands – and pairs it with alpha-hydroxy acid for gentle whitening. The fruity flavor is a fun change from the usual mint, and it’s great if you’re dealing with stains or enamel sensitivity. Of course, it doesn’t have any fluoride or harsh ingredients too.

The compact tube makes it easy to throw in a bag, and the ampoule-style formula really does feel next-level. If you’re curious about hydroxyapatite but want something a little more high-tech, start here.

Price: $17.99 for a 3-pack
Get it on Amazon

Himalaya Botanique Whitening+ Hydroxyapatite Toothpaste

Himalaya’s take on hydroxyapatite toothpaste blends gentle ingredients with a solid clean. The mint flavor is bright and refreshing, and the mix of nHA with papaya and pineapple enzymes actually works to lift stains—without any bleach or harsh abrasives. It’s fluoride-free, SLS-free, and still manages to foam and feel like a “normal” toothpaste, which I appreciated.

This brand also checks the boxes for clean living: vegan, cruelty-free, and made without artificial colors, preservatives, or fillers. If you want something plant-powered and easy on your mouth, this one’s a safe bet.

Price: $10.99 for 1 tube (4 oz)
Get it on Grove

GuruNanda Hydroxyapatite Toothpaste

This is fairly new, but it’s a good choice if you're looking for something gentle but effective. The minty jasmine-neem flavor is fresh but not overpowering, and the clean formula leaves your mouth feeling smooth and refreshed.

Sustainability-wise, the brand emphasizes natural, safe ingredients and clean formulas. While it still comes in plastic tubes, the focus on clean sourcing and a wellness-first approach earns points.

Price: $37.99 for 4-pack (4.2 oz each)
Get it on Amazon

RiseWell Natural Hydroxyapatite Toothpaste

RiseWell’s Mineral Toothpaste skips all the usual junk but still leaves your mouth feeling clean and fresh. The formula includes nano-hydroxyapatite, xylitol, and essential oils. It foams lightly, which gives it a familiar feel if you’re switching from conventional toothpaste.

It’s also vegan, gluten-free, and safe to swallow, which makes it a great pick for the whole household. Sustainability-wise, they’re still using plastic tubes, but the company is small, and they’re active about improving ingredient transparency and ethical sourcing.

Price: $12.00 for 1 tube (4 oz)
Get it on Beauty Heroes

RiseWell Kids Hydroxyapatite Toothpaste

If you’re looking for a hydroxyapatite toothpaste for kids, this one gets the job done. It’s fluoride-free, safe to swallow, and uses hydroxyapatite to protect growing teeth without any of the usual chemical extras. 

Best of all, the cake batter flavor is a huge hit for kids. Plus, you can use it yourself, too!

Price: $12.00 for 1 tube (3.4 oz)
Get it on Beauty Heroes

MOON Midnight Enamel Care Hydroxyapatite Toothpaste

MOON’s Midnight Enamel Care toothpaste feels like the evening routine upgrade I didn’t know I needed. It’s soft on the gums, has a gentle lavender-mint flavor, and uses hydroxyapatite to rebuild enamel overnight. I love that it works while I sleep – lifting surface stains without irritating my sensitive teeth. The shimmery paste is a fun touch too.

The formula skips harsh stuff like SLS, parabens, and phthalates. It’s vegan, cruelty-free, and designed with both beauty and function in mind. If you’re into thoughtful oral care with a calm, nighttime vibe, this one’s worth trying.

Price: $27.98 for 2-pack
Get it on Amazon

Primal Life Organics Dirty Mouth Mineral Toothpaste

This clay-based toothpaste from Primal Life Organics is packed with natural minerals and nano-hydroxyapatite. It swaps out the usual foaming agents and chemicals for bentonite, French green clay, and kaolin. Plus, it has colloidal silver and essential oils.

The spearmint flavor is bright and crisp, and despite the name, it doesn't taste like dirt. It’s free from SLS, fluoride, preservatives, and synthetic anything. If you’re into mineral-based care with a bold, earthy twist, this might be the one.

Price: $19.79 for 1 tube (4 oz)
Get it on Amazon

How Hydroxyapatite Toothpaste Compares to Fluoride

Fluoride helps prevent cavities, that’s not in question. But some people don’t want it in their toothpaste. They worry about long-term effects or overexposure.

That’s where hydroxyapatite steps in. It repairs enamel, reduces sensitivity, and helps fight cavities without the same concerns.

Studies show that hydroxyapatite toothpaste works just as well as fluoride toothpaste in many cases. Sometimes even better for sensitivity.

It’s also non-toxic. You don’t need a poison warning label on hydroxyapatite toothpaste. That’s a big deal for parents or anyone trying to avoid harsh chemicals. So, if you want something safe, simple, and still effective, this might be it.

Who Should Try Hydroxyapatite?

If this sounds like you:

• Teeth feeling sensitive
• Trying to avoid fluoride
• Want whiter, smoother enamel

Then hydroxyapatite options like Boka toothpaste could be worth trying. Even kids can use it, as well as people with health concerns and those with medications.

What to Look for in a Hydroxyapatite Toothpaste

Not all formulas are the same. For example, some use nano-hydroxyapatite while others use micro. Here's what matters:

• Form of hydroxyapatite. Nano is more researched at the moment but micro is less processed. Both are known to show results.
  
  
• Other ingredients. Look for short, clean lists to make sure that you’re getting a product that’s truly right for you.
  
  
• Fluoride-free. Most of these are fluoride-free since that’s one of their main differences, but double-check just for sure.
  
  
• Vegan or cruelty-free. Many companies are pushing sustainable practices in the industry.
  
  
• Taste and texture. Simple: you’ll use it more if you like it.
  
  

Some also include extras like xylitol, prebiotics, or clay. Those can help balance oral bacteria or boost freshness but they’re not required.

Is It Good for Long-Term Use?

So far, yes. It’s been used in Japan for decades. Dentists there trust it. There’s no known risk from using it daily. 

That said, not every dentist recommends it yet. Some still lean toward fluoride for cavity control. But more are starting to see it as a valid option. 

If you’re curious, talk to your dentist. Ask how it compares based on your teeth and habits. They might surprise you.

Final Thoughts

You want clean teeth, strong enamel, and fewer harsh chemicals. That’s why hydroxyapatite toothpaste is having a moment. So, try it for a few weeks, perhaps with your AI toothbrush. Look at your teeth, see how they feel.

After all, sometimes the best changes are the small ones you stick with.

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