The Truth About Mouth Wrinkles (And What to Use That Works)

If you’ve caught yourself Googling “how to get rid of mouth wrinkles” at 1 AM, well, you’re not alone.

I did it too. Half-asleep, moisturizer still tacky on my face, squinting at photos of laugh lines and nasolabial folds wondering, “Wait… were those always there?”

Mouth wrinkles can sneak up on you. One day it’s a faint crease you chalk up to dehydration. The next, it’s still there, even after exfoliating and loading up on serums. And if you smile a lot (like I do), they show up even faster.

The thing is, it’s not just about aging. A lot of these lines come from expression, lifestyle habits, and how your skin naturally loses collagen starting in your mid-20s. So no, you’re not imagining it, and you’re definitely not alone for wanting to do something about it.

This guide breaks down what causes mouth wrinkles, what actually helps reduce them, and how to stop them from getting deeper.

Why do mouth wrinkles happen so early?

Hre's the sad truth: Even if you’ve done everything “right,” skin aging is normal. And that’s okay.

Here are some reasons why mouth wrinkles develop.

• Repeated movement. Smiling, talking, chewing, frowning – all these facial motions create lines around the mouth over time.
  
  
• Loss of collagen and elasticity. From our mid-20s, collagen production starts dropping. That leads to thinner skin and more visible creases.
  
  
• Sun exposure. UV rays break down collagen and elastin, speeding up wrinkle formation especially if you didn’t wear SPF religiously in your teens.
  
  
• Lifestyle factors. Smoking, dehydration, poor sleep, and high sugar intake can also make lines appear sooner or deeper.

Best Products For Mouth Wrinkles in 2025

If you're ready to do something about those fine lines (and maybe even prevent more), here's what’s actually worth buying.

(Note: We may get a commission when you buy from any of these links. Rest assured that it doesn’t affect our opinions in any way.)

1. SkinMedica Retinol 0.5 Complex

Developed by dermatologist Dr. Richard Fitzpatrick, the SkinMedica retinol serum is highly recommended by skincare experts – and for good reason. 

It improves texture, reduces dullness, and helps soften the look of fine lines around the mouth and face. It’s strong enough to work, but not so strong that it leaves your skin peeling (as long as you start slow). 

Those with sensitive or acne-prone skin don’t have to worry about irritation with this serum. Just make sure to pair it with sunscreen.

How it works against mouth wrinkles: Retinol speeds up skin cell turnover and stimulates collagen production. Over time, that can help firm the skin around the mouth and reduce the appearance of smile lines and creases.

• Type: Serum
• Price: $80.00 for 1 fl oz
• Get it on Amazon

2. SkinMedica TNS Recovery Complex

If you’re ready to invest in something next-level, this growth factor serum is it. The TNS Recovery Complex from SkinMedica uses a patented blend of growth factors and exosomes to improve skin texture, reduce redness, and visibly smooth lines and wrinkles.

It’s pricey, but many long-time users call it a “liquid facelift.” You’ll need to be consistent, and you must wear sunscreen, but the results can be dramatic.

How it works against mouth wrinkles: The TNS formula promotes collagen synthesis and cellular renewal with fibroblast-derived growth factors. These signal the skin to repair damage, plump up fine lines, and improve firmness especially in areas like smile lines and marionette creases.

• Type: Serum
• Price: $230.00 for 1 oz
• Get it on Amazon

3. Shiseido Future Solution LX Eye and Lip Contour Regenerating Cream

This luxe refill targets stubborn wrinkles and sagging around the mouth and eyes. It’s rich, hydrating, and backed by decades of research. 

The formula blends Shiseido’s LonGenevity Complex with Enmei Herb, vitamin C, green tea, and amino acid derivatives to visibly lift and firm delicate areas. I’ve tried a lot of creams, but this one genuinely feels like it does more than just moisturize; it helps smooth fine lines and gives skin a resilient, well-rested glow. 

Bonus: it’s safe for all skin types and tested by dermatologists and ophthalmologists alike.

Added bonus: There’s also a refill available. Same ingredients, less packaging, and a little easier on the wallet.

How it works against mouth wrinkles: By boosting hydration and supporting collagen with targeted botanical and peptide ingredients, this cream helps plump and firm laugh lines while improving elasticity and smoothness over time.

• Type: Rich cream
• Price: $165 for 17 mL, $150 for the refill
• Get it on Amazon (Refill here)

4. NuSkin Tru Face Line Corrector

This peptide-powered serum is designed to reduce the look of fine lines, particularly around the mouth, eyes, and forehead. 

Compared to the other serums for mouth wrinkles here, it’s quite affordable. And yet, it does visibly smooth skin and boost elasticity with regular use. It can even fade age spots. Since it's pretty lightweight, there's no issue wearing it under makeup. 

It works well for sensitive skin, too. If you want a targeted fix for expression lines, this is a solid affordable option.

How it works against mouth wrinkles: NuSkin uses a blend of peptides that support collagen production, which helps plump and firm the skin over time. That added structure can soften the look of laugh lines and small creases around the lips with consistent use.

• Type: Serum
• Price: $61.99 for 1 fl oz
• Get it on Amazon

5. NEWKEY LED Face Mask Light Therapy

If you want visible results without pricey dermatologist visits, this FDA-cleared LED face mask might be the move. 

With 150 medical-grade LEDs and seven color modes, it tackles everything from wrinkles to breakouts. Red light (625nm) targets fine lines and helps with firmness, while blue light (465nm) is all about calming acne and reducing inflammation. 

It’s not wireless, but the 10-minute auto shut-off keeps things simple enough for a nighttime routine.

How it works against mouth wrinkles: The red light mode penetrates deeper skin layers to boost collagen and promote healing where expression lines show. You can notice softer nasolabial folds and a more even skin tone after a few weeks of consistent use, especially when paired with a serum.

• Type: LED light therapy device
• Price: $150.89
• Get it on Amazon

6. BLUMBODY Face & Forehead Wrinkle Patches

These non-silicone patches work while you sleep – smoothing out fine lines around the mouth, eyes, and forehead. They're gentle on skin, stick surprisingly well (even if you toss and turn), and feel light enough to forget they’re there. 

I tried these myself after hearing good things – and I get the hype. They’re comfy, stay put all night, and don’t feel cheap at all. I’ve even reused them a few times without losing effectiveness. 

For the price, they’re honestly such a solid find.

How it works against mouth wrinkles: By holding the skin in place overnight, the patches help relax repetitive facial movements that lead to wrinkles especially smile lines. Over time, this can soften creases and make them less noticeable without using anything invasive.

• Type: Anti-wrinkle patches
• Price: $24.48 for 165 patches
• Get it on Amazon

7. NuFACE Trinity Effective Lip & Eye Attachment

If you’re already using the NuFACE Trinity and want to target laugh lines or crow’s feet more precisely, this FDA-cleared attachment is worth a look. 

The dual wands are designed to tighten, lift, and tone the harder-to-reach areas around your mouth and eyes using microcurrent technology. It doesn’t just feel good while you use it – it genuinely gives a firmer, more sculpted appearance with consistent sessions. 

You can also track your results in the NuFACE app, which is a nice touch if you're into progress selfies.

How it works against mouth wrinkles: This attachment directs microcurrent into the muscles around the mouth, helping tone and tighten the skin. The stimulation improves circulation and collagen support, making fine lines appear less pronounced over time.

Just a heads-up: it doesn’t work with the Trinity Plus model, only the original Trinity. You’ll also need the NuFACE device and conductive gel (sold separately) for it to work.

• Type: Microcurrent attachment
• Price: $160 for 1 unit
• Get it on Amazon

Can you actually get rid of mouth wrinkles?

Not completely, but you can reduce the appearance of mouth wrinkles and stop them from getting worse. 

Thanks to technology, we’ve now got real, proven treatments that work over time. Some are topical (like retinol or peptides), some are in-office (like lasers or microneedling), and others are lifestyle-based (like better hydration or sleeping on your back). 

The key is consistency and choosing what fits your budget and comfort level.

What helps reduce mouth wrinkles?

Thankfully, there are plenty of solutions nowadays that can slow down the process or soften what’s already there.

• Retinoids or retinol. These stimulate cell turnover and collagen. Just start slow if you’re new to them.
• Peptides. Signal your skin to make more collagen. Look for products with copper peptides or Matrixyl.
• SPF. Daily sunscreen is non-negotiable. Yes, even if it’s cloudy!
• Moisture. A good humectant (like hyaluronic acid) and an occlusive layer on top can keep the area plump.
• Facial massage. Gentle massage can improve circulation and reduce tension around the mouth.
• In-office treatments. Think microneedling, chemical peels, or fillers. These work best when done by a pro and tailored to your skin.

We’ll talk more about products in the next section, so you can pick something that actually fits your routine.

Final Thoughts

If smile lines, marionette folds, or lip creases are starting to show, you’re not alone—and you’re not stuck with them. From science-backed serums and peptides to targeted tools like microcurrent devices, there are plenty of options that actually do something. 

The best approach? Consistency. Stick with products that suit your skin, give them a few weeks, and be realistic about what over-the-counter options can do.

Whether you’re just starting to notice fine lines or already dealing with deeper creases, the right products can visibly smooth, plump, and firm the area around your mouth without invasive treatments!

FAQs about mouth wrinkle products

What causes mouth wrinkles?

Mouth wrinkles usually come from repeated facial movement, collagen loss, sun damage, and natural aging. Smoking and dehydration can make them worse, too.

Can creams or serums really reduce mouth wrinkles?

They can help. Products with retinol, peptides, vitamin C, and hyaluronic acid are known to improve skin texture and reduce the appearance of lines with consistent use.

How long does it take to see results?

It depends on the product, but most users report visible improvements after 4–8 weeks of regular use. Some tools, like microcurrent devices, may offer short-term lift right away.

Do I need to use a separate product for mouth wrinkles?

Not always. Many eye creams or face serums can be used around the mouth but check the label. The skin here is delicate, so you want something that’s effective but not irritating.

Is there a way to prevent new wrinkles from forming?

Daily sunscreen, hydration, a good skincare routine, and avoiding habits like smoking can slow down the appearance of new lines. Start early and stay consistent.